Impaired Maturation of Cognitive Control in Adolescents Who Develop Major Depressive Disorder

N Vijayakumar; S Whittle; M Yücel; ML Byrne; O Schwartz; JG Simmons; NB Allen

Journal article

Impaired Maturation of Cognitive Control in Adolescents Who Develop Major Depressive Disorder

N Vijayakumar, S Whittle, M Yücel, ML Byrne, O Schwartz, JG Simmons, NB Allen

Journal of Clinical Child and Adolescent Psychology | Published : 2016

DOI: 10.1080/15374416.2014.987381

Abstract

This study examined whether development of two forms of cognitive control (proactive and reactive) between early and midadolescence was associated with the onset of major depressive disorder (MDD) during the same period and if it prospectively predicted MDD onset between mid- and late adolescence. Adolescents (N = 165) completed 3 waves of assessments, at 12 (T1), 16 (T2), and 18 (T3) years of age. Diagnostic interviews were conducted at each time point to identify three groups of adolescents: “early MDD,” those who developed MDD between early (T1) and mid- (T2) adolescence (n = 23); “late MDD,” those who developed MDD between mid- (T2) and late (T3) adolescence (n = 20); and “controls,” tho..

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University of Melbourne Researchers

Sarah Whittle Author

Orli Schwartz Author

Julian Simmons Author

Nick Allen Author

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Grants

Awarded by Australian Research Council

Funding Acknowledgements

This research was supported by grants from the Colonial Foundation, the National Health and Medical Research Council (NHMRC; Australia; Program Grant 350241) and the Australian Research Council (Discovery Grant DP0878136). Dr. Whittle is supported by an NHMRC Career Development Fellowship (ID: 1007716). Professor Yucel is supported by an NHMRC Fellowship (ID: 1021973).